Salute to Excellence

  • Researcher: Robert Bortolussi, MD

    In 1991, I reported that newborn infants cannot produce two important factors needed to combat bacterial infection. These studies conducted at Dalhousie University were the culmination of 10 years of research resulting from an outbreak of a bacterial infection in the maritime provinces

  • Researcher: Louis Siminovitch, PhD, DSc

    Although molecular biology encompasses many disciplines, such as biochemistry, its base lies in the field of genetics. The dominant role of genetics in development of knowledge in biology and medicine can be likened to that of mathematics in physics, engineering and chemistry.

  • Researcher: Dr. Irving B. Fritz*

    While a post-doctoral fellow in the laboratory of Professor Einar Lundsgaard in Copenhagen, Denmark many years ago (1954), I was investigating metabolic relationships between muscle and liver. Professor Lundsgaard had previously observed that optimal liver function was dependent upon unknown factors provided by muscle. In following up these findings, I discovered that carnitine in muscle was active in increasing the oxidation of fatty acids by liver, thereby increasing the energy supply to the liver and improving its function.

  • Researcher: Victor Chernick, MD, FRCPC

    Since July 1991, surfactant replacement therapy has been approved by the HPB for the treatment of prematurely born babies who have severe lung disease (Hyaline Membrane Disease or HMD) caused by insufficient surfactant in the lung.

  • Researcher: David A. Boyes, OC, OBC

    It should be borne in mind that the classic way of evaluating a disease is to follow it, as soon as it is recognized, and see what it will turn out to be over time. This method was not considered to be a reasonable way to proceed in this case because it would mean patients would develop invasive cancer, while we were observing them, if our thesis was correct.

  • Researcher: Peter Vadas, MD, PhD, FRCPC, FACP

    Septic shock is a syndrome consisting of a fall in blood pressure, impaired ability of the blood to clot and damage to organ systems including kidneys, liver and lungs. It is caused by the presence of large numbers of bacteria in the bloodstream. Septic shock is becoming increasingly common in the North American population.

    The studies Dr. Waldemar Pruzanski and I have undertaken over the past 12 or so years stem from earlier work I had done as a PhD candidate in the late 1970s in Experimental Pathology at the University of Toronto.

  • Researcher: A.M. Albisser, BEng, MASc, PhD

    My colleagues and I developed the world's first artificial pancreas. We showed that this device can help people with difficult diabetes.

    My colleagues and I developed the world's first artificial pancreas. We showed that this device can help people with difficult diabetes. The original instrument, the size of two filing cabinets, was tested at the University of Toronto in the early 1970s with Professor Bernard Leibel, and my students at the time.

  • Researcher: Heinz E. Lehmann, MD *

    In the spring of 1953, while working as a psychiatrist at the Douglas Hospital (then Verdun Protestant Hospital) in Montreal, I came across an article in a French medical journal that reported interesting findings with a new drug. At that time, there were no drugs that were effective in the treatment of major mental illnesses such as schizophrenic psychosis or manic-depressive disorder.

  • Researcher: Claude De Montigny, MD, PhD, FRCPC

    About one-third of depressed patients do not respond satisfactorily to antidepressant drugs. Until recently, electroconvulsive therapy was considered as the treatment of choice for these patients.

    About one-third of depressed patients do not respond satisfactorily to antidepressant drugs. Until recently, electroconvulsive therapy was considered as the treatment of choice for these patients.

  • Researcher: Herbert Jasper, OC, MDCM *

    It was in 1926, at the age of 20, that I decided to devote my life to studies of the brain. Being the son of a minister of the church and a scholarly social philosopher, and influenced by Professors of philosophy and psychology at Willamette University in Oregon, with experience as a student visitor at the Oregon State Mental Hospital, I was fascinated with the problems of how the brain could control the mind and behaviour, and what human tragedies occurred when there was loss of this control.

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